Tanshinone IIA Improves Acute Gouty Arthritis in Rats through Regulating Neutrophil Activation and the NLRP3 Inflammasome

Figure 5

TIIA inhibited the formation of MPO, NE, and CitH3. (a–c) Release of MPO, NE, and CitH3 by immunohistochemistry analysis in vivo, original magnification: ×400. Arrows indicate positive signals. (d–f) Immunofluorescence analyses of MSU-induced MPO, NE, and CitH3 expression in vitro.