circ_000166/miR-296 Aggravates the Process of Diabetic Renal Fibrosis by Regulating the SGLT2 Signaling Pathway in Renal Tubular Epithelial Cells

Figure 1

The expression of circ_000166 in the kidney tissue of diabetic renal fibrosis model mice is increased. At 0, 4, 8, 12, and 16 weeks, (a) blood sugar level, (b) weight, (c) the ratio of kidney-to-body weight, and (d) urine protein levels of the normal control group and T1DM group mice were measured. (e) The expression levels of circ_000166 in the kidney tissues of the two groups of mice were detected by qRT-PCR, and (f, g) the expression levels of collagen IV in the kidney tissues of the two groups of mice were detected by qRT-PCR and western blot. The data are expressed as (control group (), DN group ()). , , and .

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