Research Article

Prognostic Value of Plasma Cold-Inducible RNA-Binding Protein in Patients with Acute Coronary Syndrome

Table 1

Baseline characteristics of study patients with ACS.

Low CIRPHigh CIRP
( pg/ml)( pg/ml)
Characteristic value

Age (years)0.594
Male (%)120 (75.0)123 (76.9)0.794
Current smoker (%)62 (38.8)94 (58.8)0.001
Hypertension (%)96 (60.0)104 (65.0)0.419
Diabetes mellitus (%)44 (27.5)38 (23.8)0.522
Hyperlipidemia (%)29 (18.1)23 (14.4)0.449
Previous MI (%)8 (5.0)6 (3.8)0.786
Previous revascularization (%)26 (16.3)31 (19.4)0.559
Previous stroke (%)16 (10.0)32 (20.0)0.018
Systolic blood pressure (mmHg)0.952
Heart rate (beats/min)0.002
LVEF (%)<0.001
In-hospital PCI147 (91.9)149 (93.1)0.832
Total cholesterol (mmol/l)0.009
HDL-cholesterol (mmol/l)0.047
LDL-cholesterol (mmol/l)<0.001
Triglyceride (mmol/l)0.322
Fasting glucose (mmol/l)0.003
eGFR (mlmin-1(1.73 m2)-1)0.072
Multivessel coronary artery lesion (≥2)77 (48.1)96 (60.0)0.043
Left main coronary artery lesion15(9.4)15 (9.4)1.0
GRACE score<0.001
Medication at discharge
 Aspirin (%)156 (97.5)157 (98.1)1.0
 Clopidogrel/ticagrelor (%)155 (96.9)160 (100)0.061
 Statins (%)156 (97.5)156 (97.5)1.0
 Beta-blockers (%)77 (48.1)83 (51.9)0.576
 ACEI/ARB (%)60 (37.5)74 (46.3)0.141

Data shown are (%) or . ACS: acute coronary syndrome; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; CIRP: cold-inducible RNA-binding protein; eGFR: estimated glomerular filtration rate; GRACE: the Global Registry of Acute Coronary Events; HDL: high-density lipoprotein; LVEF: left ventricular ejection fraction; LDL: low-density lipoprotein; MI: myocardial infarction; PCI: percutaneous coronary intervention.