Identification of the Potential Correlation between Tumor Protein 73 and Head and Neck Squamous Cell Carcinoma

Table 2

Analysis of TP73-correlated genes functional terms.

ID	Description	setSize	enrichmentScore	NES	value	p.adjust	values	Rank	leading_edge
REACTOME_CELL_CYCLE	REACTOME_CELL_CYCLE	234	0.655	2.554	0.001	0.021	0.018	592	Tags=53%, list=19%, signal=46%
REACTOME_CELL_CYCLE_MITOTIC	REACTOME_CELL_CYCLE_MITOTIC	183	0.645	2.435	0.001	0.021	0.018	592	Tags=55%, list=19%, signal=48%
REACTOME_M_PHASE	REACTOME_M_PHASE	115	0.599	2.161	0.001	0.021	0.018	592	Tags=50%, list=19%, signal=42%
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53	114	0.491	1.766	0.001	0.021	0.018	698	Tags=34%, list=22%, signal=28%
REACTOME_DNA_REPAIR	REACTOME_DNA_REPAIR	111	0.603	2.159	0.001	0.021	0.018	857	Tags=59%, list=27%, signal=44%
REACTOME_CELL_CYCLE_CHECKPOINTS	REACTOME_CELL_CYCLE_CHECKPOINTS	89	0.723	2.519	0.001	0.021	0.018	439	Tags=57%, list=14%, signal=51%
REACTOME_MITOTIC_PROMETAPHASE	REACTOME_MITOTIC_PROMETAPHASE	82	0.640	2.212	0.001	0.021	0.018	592	Tags=56%, list=19%, signal=47%
REACTOME_SIGNALING_BY_RHO_GTPASES	REACTOME_SIGNALING_BY_RHO_GTPASES	94	0.512	1.790	0.001	0.021	0.018	288	Tags=33%, list=9%, signal=31%
REACTOME_REGULATION_OF_TP53_ACTIVITY	REACTOME_REGULATION_OF_TP53_ACTIVITY	68	0.519	1.745	0.002	0.021	0.018	698	Tags=37%, list=22%, signal=29%
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR	REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR	66	0.642	2.150	0.002	0.021	0.018	818	Tags=62%, list=26%, signal=47%
REACTOME_RHO_GTPASE_EFFECTORS	REACTOME_RHO_GTPASE_EFFECTORS	65	0.587	1.960	0.002	0.021	0.018	526	Tags=51%, list=17%, signal=43%
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	51	0.714	2.289	0.002	0.021	0.018	474	Tags=63%, list=15%, signal=54%
REACTOME_MITOTIC_G2_G2_M_PHASES	REACTOME_MITOTIC_G2_G2_M_PHASES	51	0.564	1.809	0.002	0.021	0.018	592	Tags=57%, list=19%, signal=47%
WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR	WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR	49	0.651	2.082	0.002	0.021	0.018	687	Tags=57%, list=22%, signal=45%
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	46	0.696	2.196	0.002	0.021	0.018	463	Tags=57%, list=15%, signal=49%
REACTOME_BIOLOGICAL_OXIDATIONS	REACTOME_BIOLOGICAL_OXIDATIONS	20	-0.718	-2.068	0.003	0.031	0.025	547	Tags=60%, list=18%, signal=50%
REACTOME_TRANSPORT_OF_SMALL_MOLECULES	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	54	-0.560	-1.996	0.003	0.032	0.027	416	Tags=31%, list=13%, signal=28%
REACTOME_ION_CHANNEL_TRANSPORT	REACTOME_ION_CHANNEL_TRANSPORT	17	-0.691	-1.906	0.005	0.043	0.036	153	Tags=41%, list=5%, signal=39%
WP_CALCIUM_REGULATION_IN_THE_CARDIAC_CELL	WP_CALCIUM_REGULATION_IN_THE_CARDIAC_CELL	17	-0.684	-1.887	0.005	0.043	0.036	206	Tags=41%, list=7%, signal=39%
REACTOME_MUSCLE_CONTRACTION	REACTOME_MUSCLE_CONTRACTION	14	-0.716	-1.851	0.005	0.043	0.036	379	Tags=57%, list=12%, signal=50%
KEGG_INSULIN_SIGNALING_PATHWAY	KEGG_INSULIN_SIGNALING_PATHWAY	21	-0.628	-1.834	0.003	0.031	0.025	778	Tags=48%, list=25%, signal=36%
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION	KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION	11	-0.749	-1.833	0.005	0.043	0.036	489	Tags=82%, list=16%, signal=69%
WP_RAS_SIGNALING	WP_RAS_SIGNALING	28	-0.564	-1.757	0.005	0.044	0.036	356	Tags=29%, list=11%, signal=26%
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES	REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES	36	-0.534	-1.745	0.005	0.045	0.038	381	Tags=42%, list=12%, signal=37%
REACTOME_METABOLISM_OF_LIPIDS	REACTOME_METABOLISM_OF_LIPIDS	107	-0.426	-1.685	0.003	0.032	0.027	526	Tags=27%, list=17%, signal=23%
PID_BARD1_PATHWAY	PID_BARD1_PATHWAY	19	0.669	1.730	0.005	0.043	0.036	504	Tags=53%, list=16%, signal=44%
REACTOME_REGULATION_OF_TP53_ACTIVITY	REACTOME_REGULATION_OF_TP53_ACTIVITY	68	0.519	1.745	0.002	0.021	0.018	698	Tags=37%, list=22%, signal=29%
REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	10	0.783	1.749	0.005	0.043	0.036	370	Tags=60%, list=12%, signal=53%
REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	29	0.618	1.757	0.005	0.043	0.036	463	Tags=48%, list=15%, signal=41%
REACTOME_POLYMERASE_SWITCHING	REACTOME_POLYMERASE_SWITCHING	10	0.789	1.763	0.003	0.033	0.027	338	Tags=70%, list=11%, signal=63%