Cinnamaldehyde Downregulation of Sept9 Inhibits Glioma Progression through Suppressing Hif-1α via the Pi3k/Akt Signaling Pathway

Figure 4

CA inhibits the expression of related proteins. (a) U87 and U251 cells were treated with CA (4 and 8 μg/ml) for 24 hours. The expression levels of Hif-1α, Sept9, Akt, and p-Akt were detected by Western blot analysis, and β-actin was used as a loading control. (b–e) Statistical results of the expressions of Hif-1α, Sept9, Akt, and p-Akt. (f) The expression levels of LC3B were detected using Western blot analysis, and β-actin was used as a loading control. The results of a minimum of three independent trials are presented as . and compared to the control group.

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