Research Article

Partial-Methylated HeyL Promoter Predicts the Severe Illness in Egyptian COVID-19 Patients

Table 3

Comparison between the mean level of inflammatory markers and methylation status of the promoter of HeyL gene in COVID-19 patients.

COVID-19 patientsControl subjects
Proinflammatory markersPartial-methylated Unmethylated 1 valuePartial-methylated Unmethylated P2 value

PLR0.0210.76
CRP (mg/L)0.0440.133
Ferritin (ng/ml)0.0480.077
D-dimer (μg/ml)0.0260.21

1: significant value for comparing between the mean levels of inflammatory markers in COVID-19 patients according to methylation status of HeyL promoter. 2: significant value for comparing between the mean levels of inflammatory markers in control subjects according to methylation status of HeyL promoter. Statistically significant at .