Research Article
Alpha-Fetoprotein Ratio Predicts Alpha-Fetoprotein Positive Hepatocellular Cancer Patient Prognosis after Hepatectomy
Table 1
The clinical feature of patients in training cohort and validation cohort.
| | Training cohort | Validation cohort | value |
| | Number | 439 | 440 | | | Age (year) | | | 0.420 | | Gender | | | | | Male | 374 (85.2) | 387 (88.0) | 0.230 | | Female | 65 (14.8) | 53 (12.0) | | | Smoking history, (%) | | | | | Yes | 193 (44.0) | 203 (46.1) | 0.792 | | No | 246 (56.0) | 237 (53.9) | | | Alcohol history, (%) | | | | | Yes | 93 (21.2) | 109 (24.8) | 0.206 | | No | 346 (78.8) | 331 (75.2) | | | HBsAg, (%) | | | | | Positive | 380 (86.6) | 371 (84.3) | 0.346 | | Negative | 59 (13.4) | 69 (15.7) | | | Cirrhosis, (%) | | | | | Yes | 426 (97.0) | 433 (98.4) | 0.173 | | No | 13 (3.0) | 7 (1.6) | | | Child-Pugh score | | | 0.321 | | Child-Pugh class | | | | | A | 431 (98.2) | 437 (99.3) | 0.128 | | B | 8 (1.8) | 3 (0.7) | | | MELD score | | | 0.207 | | ALBI score | | | 0.221 | | TNM stage, (%) | | | 0.505 | | IA | 53 (12.1) | 38 (8.6) | | | IB | 149 (33.4) | 155 (35.2) | | | II | 160 (36.4) | 160 (36.4) | | | IIIA | 34 (7.7) | 36 (8.2) | | | IIIB | 43 (9.8) | 51 (11.6) | | | Tumor size (cm) | | | 0.950 | | Differentiation, (%) | | | 0.869 | | Well-moderate | 186 (42.4) | 184 (41.8) | | | Poor-undifferentiated | 253 (57.6) | 256 (58.2) | | | Microscopic vascular invasion, (%) | | | 0.289 | | Yes | 182 (41.5) | 198 (45.0) | | | No | 257 (58.5) | 242 (55.0) | | | Macroscopic vascular invasion, (%) | | 0.740 | | Yes | 41 (9.3) | 44 (10.0) | | | No | 388 (90.7) | 396 (90.0) | | | Tumor multiplicity, (%) | | | 0.296 | | Single | 349 (79.5) | 362 (82.3) | | | Multiple | 90 (20.5) | 78 (17.7) | | | AFP before hepatectomy (ng/μl) | | | 0.124 | | AFP after hepatectomy (ng/μl) | | | 0.753 | | AFP ratio | | | 0.892 |
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