Research Article

Alpha-Fetoprotein Ratio Predicts Alpha-Fetoprotein Positive Hepatocellular Cancer Patient Prognosis after Hepatectomy

Table 3

Univariate and multivariate analyses of the disease-free survival of AFP-positive HCC patients.

UnivariateMultivariate
HR (95% CI) valueHR (95% CI) value

Gender (male)1.467 (1.100-1.955)0.0091.231 (0.921-1.646)0.160
1.168 (0.980-1.392)0.083
Smoking1.134 (0.951-1.352)0.161
Drinking1.216 (0.994-1.487)0.057
HBV infected0.885 (0.692-1.131)0.330
Cirrhosis1.146 (0.646-2.032)0.641
Child-Pugh A0.777 (0.368-1.639)0.508
TNM stage III2.397 (1.959-2.933)<0.0010.779 (0.549-1.105)0.162
1.885 (1.581-2.247)<0.0010.697 (0.553-0.878)0.002
1.785 (1.458-2.185)<0.0010.828 (0.644-1.065)0.141
Differentiation poor1.229 (1.027-1.469)0.0241.110 (0.927-1.330)0.257
Microscopic vascular invasion1.876 (1.573-2.238)<0.0011.472 (1.220-1.776)<0.001
Macroscopic vascular invasion2.316 (1.788-3.000)<0.0011.537 (1.055-2.240)0.025
Tumor multiplicity1.730 (1.411-2.121)<0.0011.325 (1.029-1.706)0.029
0.964 (0.788-1.180)0.725
1.104 (0.918-1.328)0.295
1.572 (1.308-1.888)<0.0011.710 (1.422-2.056)<0.001