Effects of Escin on Oxidative Stress and Apoptosis of H9c2 Cells Induced by H₂O₂

Figure 5

Escin inhibited the NF-κB pathway. (a) In the H₂O₂ treatment group, the expression of p65 and IκKα increased, and the expression of IκB-α decreased. In the H₂O₂+escin group, the expression of p65 and IκKα decreased, and the expression of IκB-α increased. (b) Statistical results of protein level of p65 ( vs. control; ^# vs. H₂O₂, ). (c) Statistical results of protein level of IκKα ( vs. control; ^# vs. H₂O₂, ). (d) Statistical results of protein level of IκB-α ( vs. control; ^# vs. H₂O₂, ). (e) Expression of p65 mRNA in three groups ( vs. control; ^# vs. H₂O₂, ). (f) Expression of IκKα mRNA in three groups ( vs. control; ^# vs. H₂O₂, ). (g) Expression of IκB-α mRNA was consistent with the results of Western blot ( vs. control; ^# vs. H₂O₂, ).

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