Research Article
Effects of Metformin on Renal Function, Cardiac Function, and Inflammatory Response in Diabetic Nephropathy and Its Protective Mechanism
Table 1
Patients’ characteristic profile (
).
| Index | Experimental group () | Control group () | | |
| Average age (years) | | | 1.441 | 0.531 | Average disease duration (years) | | | 2.475 | 0.634 | Urine albumin/creatinine ratio (ACR, mg/g) | | | 5.245 | 0.548 | Fasting blood glucose (mmol/L) | | | 3.564 | 0.685 | HbA1c (%) | | | 2.475 | 0.365 | Triglycerides (TG, mmol/L) | | | 1.454 | 0.254 | Total cholesterol (TC, mmol/L) | | | 3.457 | 0.541 | Low-density lipoprotein cholesterol (LDL-C, mmol/L) | | | 5.456 | 0.477 | High-density lipoprotein cholesterol (HDL-C, mmol/L) | | | 1.045 | 0.698 | Serum uric acid (mmol/L) | | | 3.745 | 0.371 | AST (U/L) | | | 2.475 | 0.654 | ALT (U/L) | | | 2.315 | 0.638 | Glomerular filtration rate (GFR [ml−1 min−11 (1.73 m2)−11]) | | | 1.457 | 0.638 |
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