Research Article

Effects of Metformin on Renal Function, Cardiac Function, and Inflammatory Response in Diabetic Nephropathy and Its Protective Mechanism

Table 1

Patients’ characteristic profile ().

IndexExperimental group ()Control group ()

Average age (years)1.4410.531
Average disease duration (years)2.4750.634
Urine albumin/creatinine ratio (ACR, mg/g)5.2450.548
Fasting blood glucose (mmol/L)3.5640.685
HbA1c (%)2.4750.365
Triglycerides (TG, mmol/L)1.4540.254
Total cholesterol (TC, mmol/L)3.4570.541
Low-density lipoprotein cholesterol (LDL-C, mmol/L)5.4560.477
High-density lipoprotein cholesterol (HDL-C, mmol/L)1.0450.698
Serum uric acid (mmol/L)3.7450.371
AST (U/L)2.4750.654
ALT (U/L)2.3150.638
Glomerular filtration rate (GFR [ml−1 min−11 (1.73 m2)−11])1.4570.638