Research Article

Lack of Association between Epidermal Growth Factor or Its Receptor and Reflux Esophagitis, Barrett’s Esophagus, and Esophageal Adenocarcinoma: A Case-Control Study

Figure 1

The function of studied polymorphisms based on previous studies; allele A of +61 A>G epidermal growth factor (rs4444903) polymorphism leads to a reduction of EGF mRNA expression, and allele G of +142285 G>A EGF receptor (EGFR, rs2227983) polymorphism increases the activity of EGFR [24, 25].