Research Article
Lack of Association between Epidermal Growth Factor or Its Receptor and Reflux Esophagitis, Barrett’s Esophagus, and Esophageal Adenocarcinoma: A Case-Control Study
Table 1
Demographic data of subpopulations analyzed in individual partial analyses (genetic association study, EGF/EGFR mRNA expressions, and EGF plasma levels).
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BE: Barrett’s esophagus; EAC: esophageal adenocarcinoma; GERD: gastroesophageal reflux disease group; NERD: nonerosive reflux disease group; RE: reflux esophagitis; Group 1: patients with diagnosis RE, BE, or EAC determined by a pathologist; Group 2: patients without macroscopical changes of the esophageal mucosa and with/without NERD (including healthy individuals); aincluded 8 healthy individuals; bincluded patients with RE, BE, and EAC; #Group 2 vs. RE vs. BE vs. EAC comparison; §Group 2 vs. Group 1 comparison. |