Predicted Immune-Related Genes and Subtypes in Systemic Lupus Erythematosus Based on Immune Infiltration Analysis

Figure 11

LASSO feature screening of 65 SLE-related genes. (a, b) LASSO analysis results of SLE_WB and SLE_PBMC. Each line in the figure represents a gene. When the gene tends to 0, the larger the value of the abscissa (log lambda), the more critical the gene is. (c, d) Cross-validation results of SLE_WB and SLE_PBMC models. There are two dotted lines in the figure, one is the value lambda.min when the mean square error is the smallest, and the other is the value lambda.1se which is one standard error when the mean square error is the smallest. These two values can be selected according to the analysis requirements. One, the number corresponding to the dotted line is the result of the number of screened genes.

(a) SLE_WB

(b) SLE_PBMC

(c) SLE_WB

(d) SLE_PBMC