Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage

Table 4

Univariate analysis of elevated myocardial enzymes in ICH. Significant values () are in bold.

Variable	Entire cohort ()	Elevated CK ()	value	Elevated CKMB ()	value	Elevated LDH ()	value	Elevated hs-cTnT ()	value
Age (SD)	61.23 (13.64)	60.58 (13.63)	0.675	58.42 (13.57)	0.070	59.66 (14.20)	0.200	64.91 (14.81)	0.003
Male (%)	136 (65.38)	42 (73.68)	0.122	43 (75.44)	0.061	49 (61.25)	0.322	51 (64.56)	0.844
History of hypertension	140 (67.31)	39 (68.42)	0.833	39 (68.42)	0.833	54 (67.50)	0.963	57 (72.15)	0.244
History of type 2 diabetes	16 (7.69)	5 (8.77)	0.720	4 (7.02)	0.822	4 (5.00)	0.249	11 (13.92)	0.008
History of cerebrovascular diseases	32 (15.38)	12 (21.05)	0.164	10 (17.54)	0.596	10 (12.50)	0.362	14 (17.72)	0.465
History of coronary heart disease	11 (5.29)	3 (5.26)	0.992	4 (7.02)	0.494	5 (6.25)	0.624	7 (8.86)	0.072
History of smoking	76 (36.54)	22 (38.60)	0.705	25 (43.86)	0.178	28 (35.00)	0.716	28 (35.44)	0.797
History of drinking	45 (21.63)	10 (17.54)	0.379	13 (22.81)	0.801	15 (18.75)	0.424	16 (20.25)	0.705
History of antiplatelet drugs	14 (6.73)	7 (12.28)	0.050	7 (12.28)	0.050	7 (8.75)	0.358	10 (12.82)	0.007
History of anticoagulant drugs	1 (0.48)	0 (0.00)	0.538	0 (0.00)	0.538	0 (0.00)	0.428	0 (0.00)	0.437
Time (IQR)	6 (21)	7 (21)	0.287	5 (6)	0.039	5 (11)	0.167	6 (21)	0.452
	60 (28.85)	37 (64.91)	0.222	30 (52.63)	<0.001	49 (61.25)	0.013	51 (64.56)	0.100
Blood glucose (IQR)	7.43 (4.04)	7.91 (3.43)	0.346	8.03 (4.09)	0.02	7.97 (4.55)	0.008	7.91 (4.61)	0.024
Basal ganglia	100 (48.08)	27 (47.37)	0.900	26 (45.61)	0.662	42 (52.50)	0.313	31 (39.24)	0.046
Lobar	62 (29.81)	20 (35.09)	0.306	18 (31.58)	0.732	23 (28.75)	0.792	28 (35.44)	0.164
Thalamus	28 (13.46)	6 (10.53)	0.446	10 (17.54)	0.289	11 (13.75)	0.923	14 (17.72)	0.159
Cerebellum	11 (5.29)	3 (5.26)	0.992	1 (1.75)	0.162	4 (5.00)	0.883	3 (3.80)	0.452
Brain stem	4 (1.92)	0 (0.00)	0.215	2 (3.51)	0.306	0 (0.00)	0.110	1 (1.27)	0.589
PIVH	1 (0.48)	0 (0.00)	0.538	0 (0.00)	0.538	0 (0.00)	0.428	1 (1.27)	0.200
Right-sided hematoma	96 (46.15)	27 (47.37)	0.829	27 (47.37)	0.829	33 (41.25)	0.262	36 (45.57)	0.895
Insular involvement	20 (9.62)	10 (17.54)	0.017	13 (22.81)	<0.001	9 (11.25)	0.527	6 (7.59)	0.439
SIVH	56 (26.92)	16 (28.07)	0.819	18 (31.58)	0.352	30 (37.50)	0.007	22 (27.85)	0.814
Hematoma  ml	87 (41.83)	31 (54.38)	0.024	30 (52.63)	0.052	43 (53.75)	0.006	36 (45.57)	0.392
Leukocytosis	8 (3.85)	0 (0.00)	0.076	3 (5.26)	0.514	3 (3.75)	0.955	0 (0.00)	0.025
Low platelet count	2 (0.96)	1 (1.75)	0.472	1 (1.75)	0.472	1 (1.25)	0.736	0 (0.00)	0.271
Abnormal hemoglobin level	3 (1.44)	1 (1.75)	0.817	1 (1.75)	0.817	2 (2.50)	0.312	1 (1.28)	0.881
Coagulation abnormalities	2 (0.96)	0 (0.00)	0.383	0 (0.00)	0.383	0 (0.00)	0.261	1 (1.28)	0.714
Mortality	17 (8.17)	6 (10.53)	0.447	8 (14.03)	0.058	8 (10.00)	0.447	10 (12.65)	0.058

ICH: intracerebral hemorrhage; SD: standard deviation; Time: time of onset on admission; GCS: Glasgow Coma Scale; PIVH: primary intraventricular hemorrhage; SIVH: secondary intraventricular hemorrhage; CK: creatine kinase; CKMB: creatine kinase-myocardial subfraction; LDH: lactic dehydrogenase; hs-cTnT: high-sensitive cardiac troponin T.