Construction and Validation of a Risk Prediction Model for Acute Kidney Injury in Patients Suffering from Septic Shock

Table 4

Multivariate logistic regression analysis of risk factors of AKI in the training cohort.

Variables	OR	95% CI	value
Gender (female vs. male)	1.41	1.13-1.77	<0.001
Ethnicity (non-Caucasian vs. Caucasian)	0.61	0.47-0.78	<0.001
Congestive heart failure (yes vs. no)	1.53	1.19-1.97	<0.001
Diabetes (yes vs. no)	1.32	1.03-1.68	0.030
Obesity (yes vs. no)	2.98	1.66-5.34	<0.001
SAPS II	1.05	1.04-1.06	<0.001
ACEI/ARBs (yes vs. no)	1.78	1.40-2.25	<0.001
Bilirubin (mg/dl)	1.08	1.03-1.12	<0.001
Creatinine (mg/dl)	1.20	1.04-1.38	0.010
BUN (mg/dl)	0.99	0.98-0.99	<0.001
Mechanical ventilation (yes vs. no)	1.69	1.33-2.15	<0.001
Constant	0.12		<0.001

OR: odds ratio; CI: confidence interval; ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin receptor blockers; SAPS II: simplified acute physiology score II; BUN: blood urea nitrogen; AKI: acute kidney injury.