A Sight of the Diagnostic Value of Aberrant Cell-Free DNA Methylation in Lung Cancer

Figure 3

Differential methylation analysis of tissue samples. (a) The hierarchical clustering heat map of DMPs detected in tissue cohort. (b) Number of hypermethylated (red) and hypomethylated (blue) positions located in different genomic features. (c) Distribution of DMPs across the whole genome. (d) Number of hypermethylated (red) and hypomethylated (blue) positions located in different CpG resort contexts. (e) Overlap of DMPs detected in tissue set 1 and 2 separately. (f) Enrichment analysis of candidate markers in different sources using XL-mHG test.

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