A Sight of the Diagnostic Value of Aberrant Cell-Free DNA Methylation in Lung Cancer

Table 3

Diagnostic marker panel derived from cfDNA samples.

DMR marker	Coefficient	Genomic location	Gene	XL-mHG value
DMR_1	-0.007012253	chr1: 12493605-12494280	VPS13D	0.012529923
DMR_2	-0.293540674	chr1: 36983119-36983235	/	1.21307E-05
DMR_3	0.145449335	chr1: 248902767-248904167	LYPD8	0.0010886
DMR_4	-0.180719422	chr3: 11651536-11651990	VGLL4	0.001477124
DMR_5	0.3167126	chr4: 1195845-1196179	SPON2	0.00018493
DMR_6	0.194881649	chr5: 139043443-139044215	CXXC5	6.8938E-05
DMR_7	0.235620277	chr9: 123688715-123689193	TRAF1	2.2204E-16
DMR_8	0.29712874	chr11: 10476242-10477461	AMPD3	0.00183147
DMR_9	0.341871604	chr17: 16319861-16320257	TRPV2	6.4709E-04
DMR_10	0.236108117	chr17: 78753273-78754372	RPTOR	0.001784

DMR markers are made up of mean methylation values of CpG sites in the corresponding DMRs.