Value of Central Venous Pressure Monitoring in the Patients with Sepsis-Associated Acute Kidney Injury

Figure 5

The construction of the structural models and the analysis of the results. (a) Nomogram plots based on the multiple logistic regression model are displayed by means of data collected from the cohorts after adjustment by PSM. The scores from each item were also summed to obtain an overall score, where greater probability of 28-day death might be detected. Calibration plots of the training set and validation set are displayed too. Calibration curves for the training set (b) and validation set (c). ROC curves of the four models for the training set (d) and validation set (e). Model A (blue line) included the following baseline characteristics: age, sex, SOFA score, APS-III score, Charlson comorbidity index, use of mechanical ventilation, use of RRT, use of vasopressors, MAP, SV, Lac, BUN, SCr, and NLR; model B (red line) included MPP in addition to all the variables of model A; model C (green line) included initial CVP level in addition to all the variables of model A; model D (orange line) included ΔCVP in addition to all the variables of model A; model E (purple line) included MPP, initial CVP level, and ΔCVP in addition to all the variables of model A. Initial CVP level measure in the first 24 hours after admission. . SOFA = sequential organ failure assessment; APS-III = acute physiology score III; RRT = renal replacement therapy; SV = stroke volume; MAP = mean arterial pressure; BUN = blood urea nitrogen; SCr = serum creatinine; NLR = neutrophil-to-lymphocyte ratio; Lac = lactic acid; MPP = mean perfusion pressure; CVP = central venous pressure; ROC = receiver operator characteristic.

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