Research Article
Value of Central Venous Pressure Monitoring in the Patients with Sepsis-Associated Acute Kidney Injury
Table 4
Basic characteristics of the validation set (
).
| | Variables | No CVP group
| CVP group
| SMD |
| | Age (year, mean (SD)) | 64.0 (16.1) | 64.4 (14.2) | 0.024 | | Male (%) | 2030 (47.3) | 716 (54.1) | 0.135 | | Ethnicity, (%) | | | | | African American | 615 (14.3) | 141 (10.6) | 0.129 | | Asian | 77 (1.8) | 30 (2.3) | | | Caucasian | 3153 (73.5) | 1004 (75.8) | | | Hispanic | 159 (3.7) | 45 (3.4) | | | Native American | 31 (0.7) | 7 (0.5) | | | Other/unknown | 254 (5.9) | 97 (7.3) | | | First care unit, (%) | | | | | Cardiac ICU | 278 (6.5) | 65 (4.9) | 0.414 | | CCU-CTICU | 292 (6.8) | 130 (9.8) | | | CSICU | 84 (2.0) | 19 (1.4) | | | CTICU | 102 (2.4) | 138 (10.4) | | | Med-Surg ICU | 2288 (53.3) | 632 (47.7) | | | MICU | 614 (14.3) | 162 (12.2) | | | Neuro ICU | 410 (9.6) | 71 (5.4) | | | SICU | 221 (5.2) | 107 (8.1) | | | Severity of illness (mean (SD)) | | | | | SOFA score | 7.3 (2.9) | 9.6 (3.2) | 0.772 | | APS-III score | 62.6 (27.8) | 81.9 (32.9) | 0.635 | | Charlson comorbidity index | 2.7 (1.4) | 2.8 (1.3) | 0.070 | | Hemodynamic variables measured in the first 24 hours of admission to ICU (mean (SD)) | | | | | MAP (mmHg) | 67.3 (30.3) | 64.6 (28.8) | 0.093 | | HR (bpm) | 85.4 (18.3) | 89.3 (18.7) | 0.213 | | CI (L/min/m2) | 2.6 (0.7) | 2.6 (0.8) | 4.429 | | SV (mL) | 62.0 (29.6) | 63.1 (21.6) | 0.098 | | Lac (mmol/L) | 2.3 (2.5) | 3.3 (3.6) | 0.328 | | Inflammatory indicators measured in the first 24 hours of admission to ICU (mean (SD)) | | | | | WBC (×109/L) | 11.4 (8.4) | 14.3 (10.8) | 0.296 | | NLR | 10.6 (15.6) | 13.5 (16.0) | 0.181 | | Renal function index measured in the first 24 hours of admission to ICU | | | | | BUN (mg/dL) | 30.8 (24.9) | 37.2 (25.7) | 0.255 | | SCr (mg/dL) | 2.0 (2.1) | 2.3 (2.0) | 0.141 | | AKI stage | | | | | I | 3833 (89.6) | 1172 (88.7) | 0.027 | | II | 231 (5.4) | 77 (5.8) | | | III | 216 (5.0) | 72 (5.5) | | | Interventions in the first 24 hours of admission to ICU, (%) | | | | | MV use | 1176 (27.4) | 785 (59.3) | 0.679 | | Vasopressor use | 16 (0.4) | 15 (1.1) | 0.088 | | RRT use | 11 (0.3) | 9 (0.7) | 0.062 |
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CVP = central venous pressure; SMD = standard mean difference; CVICU = cardiovascular intensive care unit; CCU = coronary care unit; MICU = medical intensive care; SICU = surgical intensive care unit; TSICU = trauma surgical intensive care unit; SOFA = sequential organ failure assessment; APS-III = acute physiology score III; MAP = mean arterial pressure; HR = heart rate; CI = cardiac index; SV = stroke volume; Lac = lactic acid; WBC = white blood cell; NLR = neutrophil-to-lymphocyte ratio; BUN = blood urea nitrogen; SCr = serum creatinine; AKI = acute kidney injury; MV = mechanical ventilation; RRT = renal replacement therapy.
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