Research Article
Identification of Significant Genes and Pathways for the Chronic and Subacute Cutaneous Lupus Erythematosus via Bioinformatics Analysis
Table 3
The top hub genes of SCLE.
| Gene symbol | Description | Degree of connectivity |
| STAT1 | Signal transducer and activator of transcription 1 | 88 | CXCL10 | C-X-C motif chemokine ligand 10 | 78 | IRF7 | Interferon regulatory factor 7 | 70 | ISG15 | ISG15 ubiquitin-like modifier | 68 | RSAD2 | Radical S-adenosyl methionine domain-containing 2 | 64 | IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | 64 | OASL | 2-5-Oligoadenylate synthetase like | 62 | GBP1 | Guanylate-binding protein 1 | 62 | OAS1 | 2-5-Oligoadenylate synthetase 1 | 60 | OAS2 | 2-5-Oligoadenylate synthetase 2 | 60 |
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