Research Article

Identification of Significant Genes and Pathways for the Chronic and Subacute Cutaneous Lupus Erythematosus via Bioinformatics Analysis

Table 3

The top hub genes of SCLE.

Gene symbolDescriptionDegree of connectivity

STAT1Signal transducer and activator of transcription 188
CXCL10C-X-C motif chemokine ligand 1078
IRF7Interferon regulatory factor 770
ISG15ISG15 ubiquitin-like modifier68
RSAD2Radical S-adenosyl methionine domain-containing 264
IFIT3Interferon-induced protein with tetratricopeptide repeats 364
OASL2-5-Oligoadenylate synthetase like62
GBP1Guanylate-binding protein 162
OAS12-5-Oligoadenylate synthetase 160
OAS22-5-Oligoadenylate synthetase 260