The Recurrent-Specific Regulation Network of Prognostic Stemness-Related Signatures in Low-Grade Glioma
Table 2
Summary of 7 most significant biomarkers in external validation.
(a)
NCAPG
AURKA
E2F1
TP53
RB1
GEPIA
Expression: - Survival: ,
Expression: - Survival: ,
Expression: - Survival: ,
Expression: high Survival: ,
Expression: high Survival: ,
Oncomine
Expression: high
Expression: high
Expression: NA
Expression: high
Expression: high
cBioPortal
Survival:
Survival:
Survival:
Survival:
Survival:
UALCAN
Grade: Survival:
Grade: Survival:
Grade: Survival:
Grade: Survival:
Grade: Survival:
LinkedOmics
Survival:
Survival:
Survival:
Survival:
Survival:
TISIDB
Survival: Grade: ,
Survival: Grade: ,
Survival: Grade: ,
Survival: Grade: ,
Survival: Grade: ,
(b)
CCND1
CDK4
Results
Expression: high Survival: ,
Expression: high Survival: ,
TP53, RB1, CCND1, and CDK4 are significantly upregulated in LGG. The high expression of NCAPG, AURKA, E2F1, T53, and RB1 is correlated with worse prognosis in LGG (Figure S1).
Expression: high
Expression: high
NCAPG, AUTKA, TP53, RB1, CCND1, and CDK4 are significantly upregulated in LGG (Figure S2).
Survival:
Survival:
The high expression of NCAPG, TP53, and CDK4 is correlated with worse prognosis in LGG (Figure S3).
Grade: Survival:
Grade: Survival:
The high expression of NCAPG, AURKA, E2F1, TP53, and CCND1 is correlated with higher grade in LGG. NCAPG, AUTKA, E2F1, TP53, CCND1, and CDK4 are significantly upregulated in LGG (Figure S4).
Survival:
Survival:
The high expression of NCAPG, AURKA, E2F1, TP53, CCND1, and CDK4 is correlated with worse prognosis in LGG (Figure S5).
Survival: Grade: ,
Survival: Grade: ,
The high expression of NCAPG, AURKA, and E2F1 is correlated with worse prognosis in LGG. The high expression of NCAPG, AURKA, E2F1, TP53, RB1, CCND1, and CDK4 is correlated with higher grade in LGG (Figure S6).