The Roles of TRAF3 in Immune Responses

Figure 1

The six human TNFR-associated factor (TRAF) proteins that contain a C-terminal TRAF domain are shown. All TRAFs (except for TRAF1) contain an N-terminal RING finger domain (a signature motif of E3 RING finger ubiquitin ligase; labeled R) and several zinc finger motifs (labeled Z). The TRAF domain contains a coiled-coil region (labeled CC) and a C-terminal TRAF-C domain (also known as a meprin and TRAF homology (MATH) domain). AA: amino acids.