Ferroptosis-Related Prognostic Gene LAMP2 Is a Potential Biomarker Differential Expressed in Castration Resistant Prostate Cancer

Table 2

Cox regression for hub genes associated with overall survival of TCGA data.

Gene symbol	Cases	Univariate analysis		Multivariate analysis
		HR (95% CI)	value	HR (95% CI)	value
MDM4	495	6.424 (1.318-31.316)	0.021	5.242 (0.780-35.217)	0.088
LAMP2	495	0.119 (0.015-0.952)	0.045	0.095 (0.012-0.771)	0.028
EZH2	495	7.315 (0.919-58.246)	0.06	4.929 (0.572-42.488)	0.147
PRKCA	495	0.275 (0.058-1.318)	0.106
CDKN2A	495	3.471 (0.729-16.530)	0.118
CDCA3	495	3.300 (0.696-15.636)	0.133
GABARAPL2	495	2.814 (0.721-10.977)	0.136
CREB1	495	2.729 (0.697-10.691)	0.15
MIB2	495	3.064 (0.616-15.233)	0.171
BRD2	495	1.994 (0.552-7.203)	0.292
GABARAPL1	495	0.526 (0.135-2.047)	0.354
GJA1	495	0.544 (0.136-2.173)	0.389
EGR1	495	0.578 (0.162-2.068)	0.4
BECN1	495	1.527 (0.429-5.430)	0.513
CAV1	495	0.694 (0.164-2.928)	0.619
SCP2	495	0.896 (0.259-3.105)	0.863
LIG3	495	1.057 (0.303-3.690)	0.931
TP63	495	0.949 (0.258-3.489)	0.937
ELOVL5	495	1.000 (0.289-3.459)	0.999

HR = hazard ratio; CI = confidence interval. Multivariate regression was conducted when value <0.1.