Ferroptosis-Related Prognostic Gene LAMP2 Is a Potential Biomarker Differential Expressed in Castration Resistant Prostate Cancer

Table 3

Cox regression for hub genes associated with disease specific survival of TCGA data.

Gene symbol	Case	Univariate analysis
		HR (95% CI)	value
MDM4	495	5.498 (0.611-49.447)	0.128
BRD2	495	4.902 (0.544-44.139)	0.156
CREB1	495	4.569 (0.505-41.305)	0.176
BECN1	495	3.906 (0.436-34.947)	0.223
PRKCA	495	0.262 (0.029-2.412)	0.237
LAMP2	495	0.264 (0.029-2.419)	0.239
GABARAPL1	495	0.285 (0.032-2.567)	0.263
CDCA3	495	3.496 (0.388-31.466)	0.264
GJA1	495	0.286 (0.031-2.627)	0.269
SCP2	495	3.437 (0.383-30.816)	0.27
CDKN2A	495	3.410 (0.373-31.174)	0.277
TP63	495	0.323 (0.035-2.961)	0.318
MIB2	495	3.050 (0.316-29.407)	0.335
CAV1	495	0.357 (0.037-3.442)	0.373
GABARAPL2	495	1.793 (0.298-10.805)	0.524
EGR1	495	0.580 (0.096-3.501)	0.553
ELOVL5	495	1.484 (0.248-8.882)	0.665
LIG3	495	1.437 (0.240-8.605)	0.691
EZH2	495	513316338.157 (0.000-Inf)	0.999

HR = hazard ratio; CI = confidence interval. Multivariate regression was refused since no significance was in univariate analysis.