High-resolution omics, such as single-cell sequencing, cytometry by time-of-flight, spatial transcriptomics, and multiplexed imaging, have provided an unprecedented opportunity for accelerated biomarker discovery and subsequent clinical translation. Although accumulating research efforts are being made, the utilization of high-resolution omics for biomarker discovery and successful translation are yet to flourish. Furthermore, important issues throughout the pipeline of high-resolution omics-based biomarker discovery which involves sample preparation, data pre-processing, data integration, and result interpretation, are to be addressed and discussed.

In this Special Issue, we welcome submissions focusing on high-resolution omics as tools for biomarker discovery across healthcare and biology disciplines. We welcome original research and review articles.

Potential topics include but are not limited to the following:

• High-resolution omics for cancer biomarker discovery
• High-resolution omics for aging biomarker discovery
• High-resolution omics for surgery biomarker discovery
• High-resolution omics for cardiovascular disease biomarker discovery
• High-resolution omics for bone health biomarker discovery
• High-resolution omics for respiratory disease biomarker discovery
• High-resolution omics for infectious disease biomarker discovery
• High-resolution omics for neurological biomarker discovery
• High-resolution omics for gynecological biomarker discovery
• High-resolution omics for biomarker discovery in miscellaneous healthcare disciplines
• Innovation in high-resolution omics data science