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Dermatology Research and Practice
Volume 2009 (2009), Article ID 607682, 4 pages
Case Report

Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians

Department of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, Germany

Received 4 February 2009; Accepted 24 April 2009

Academic Editor: Iris Zalaudek

Copyright © 2009 Sven Neynaber et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.