Dermatology Research and Practice / 2010 / Article / Fig 2

Review Article

A New Perspective on Intercalated Disc Organization: Implications for Heart Disease

Figure 2

Model for cadherin-based area composita in the heart. T-catenin recruits desmosomal protein, plakophilin- (PKP-) 2 to hybrid adhering junction (left drawing), thereby forming, together with desmosome (right drawing), an area composita, which is an enforced, mixed-type junctional structure attached to both the actin cytoskeleton and the intermediate filament (PG: plakoglobin; DP: desmoplakin).
207835.fig.002

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.