A New Perspective on Intercalated Disc Organization: Implications for Heart Disease

Table 1

The different composition of desmosomes in skin and heart.

	Skin	Heart
Desmosomal cadherins	Desmoglein (DSG) 1–4	Desmoglein (DSG)-2
	Desmocollin (DSC) 1–3	Desmocollin (DSC)-2
Armadillo proteins	Plakoglobin (PG)	Plakoglobin (PG)
	Plakophilin (PKP) 1–3	Plakophilin (PKP)-2
Plakins	Desmoplakin (DP)
	Plectin	Desmoplakin (DP)
	Envoplakin	Plectin
	Periplakin