Dermatology Research and Practice

Clinical Study

Long-Term Followup of Dermal Substitution with Acellular Dermal Implant in Burns and Postburn Scar Corrections

Table 1

Biotechnologically derived products designed to improve dermal wound repair.


Biotechnological device
Name	Composition	Manufacturer	Cellular content	Ref. no

MB-Collagen/Collagen-Klee	Porcine collagen	Medical Biomaterial Products GmbH Neustadt-Glewe, BRD	no	[2]
BGC Matrix	Porcine collagen and beta-Glucan	Brennen Medical Inc, St. Paul MN, USA	no	[3]
Promogran	Bovine collagen, regenerated oxidized cellulose	Systagenix Wound Management Ltd., Gargrave, UK	no	[4]
Biostep/Biostep Ag Collagen Matrix Dressing	Porcine collagen	Smith & Nephew Inc. St. Petersburg, FL USA	no	—
Matriderm	Bovine collagen and elastin matrix	Dr. Suwelack Skin & Health Care AG, Billerbeck, BRD	no	[5]
Alloderm regenerative tissue matrix	Freeze-dried ECM from cadaver skin	LifeCell Co., The Woodlands, TX USA	no	[6]
Glyaderm dermal replacement material	Dermal collagen-elastin matrix	Euro Skin Bank, Beverwijk, NL	no	[7]
SureDerm	Freeze-dried ECM from cadaver skin	Hans Biomed Corp., Seoul, Korea	no	[8]
Integra dermal regeneration template	Bovine collagen and GAG, with a supporting epidermal silicone sheet	Integra LifeSciences Co., Plainsboro, NJ USA	no	[9]
TransCyte/Dermagraft TC temporary, biosynthetic wound cover	Porcine collagen coated nylon mesh with human fibroblast and silicone membrane	Advanced BioHealing Inc, Westport, CT USA	yes	[11]
Dermagraft	Biodegradable polyglactin mesh with human fibroblast	Advanced BioHealing Inc, Westport, CT USA	yes	[12]
Apligraf/Graftskin living skin equivalent	Bilayered structure bovine collagen with human fibroblasts and human keratinocytes	Organogenesis Inc., Canton, MA USA and Novartis AG Basel, CH	yes	[13]
OrCel cryopreserved bilayered matrix	Bilayered structure bovine collagen with human fibroblasts and human keratinocytes	Forticell BioScience Inc., New York, NY USA	yes	[16]
StrataGraft Pathogen-free human temporary allograft	Bilayered structure: non-bovine collagen with human fibroblasts and immortalized human keratinocytes	Stratatech Corporation, Madison, WI USA	yes	[17]