Dermatology Research and Practice

Research Article

Targeted Immunotherapy with Rituximab Leads to a Transient Alteration of the IgG Autoantibody Profile in Pemphigus Vulgaris

Table 2

Profile of desmoglein 3 (Dsg3)-specific IgG autoantibodies of the pemphigus vulgaris (PV) patients before and 6 months after treatment with rituximab (Rtx).
Dsg3EC1Dsg3EC2Dsg3EC3Dsg3EC4Dsg3EC5
Time point0606060606
PV1++++++−−−−
PV2++++−−−−−−
PV3++−+−−−+−−
PV4+−−−+++−−−
PV5−−−−+−++−−
PV6+−−−−−−−−−
PV7++++−−−−−−
PV8−−−−+−−−−−
PV10−−−+−−+−−−
PV11++−−−−−−−−
PV12+++−++++−−
PV13+−−−−−+−−−
PV14+−+−−−+−+−
PV15−−−−+−−−−−
PV16−−−−−−++−−
PV17++−−−−−−−−
PV18−−−−−−+−−−
PV19++−−−−−−−−
PV20++−−−−−−−−
PV21++−−+++−−−
PV22−−−−−−+−−−
PV23−−−−−−+++−