Serum Interleukin-4 and Total Immunoglobulin E in Nonatopic Alopecia Areata Patients and HLA-DRB1 Typing

Table 4

Frequencies of selected HLA-DRB1 alleles in alopecia patients compared to controls using Chi square test.

DRB1 allele	Controls (n = 580)	Overall alopecia (n = 54)	P value	LAA (n = 18)	P value	AT/AU (n = 36)	P value
HLA-DRB1*01	5%	5.6%	.998	0%	.083	5.6%	.954
HLA-DRB1*03	19%	22.2%	.992	5.5%	.000*	16.6%	.515
HLA-DRB1*04	16%	16.7%	1.0	11.1%	.223	5.6%	.006**
HLA-DRB1*07	6%	11.1%	.31	0%	.04*	11.1%	.088
HLA-DRB1*08	2%	5.6%	.28	0%	.911	5.6%	.002**
HLA-DRB1*11	12%	22.2%	.048*	11.1%	.735	11.1%	.735
HLA-DRB1*13	16%	5.6%	.021*	0%	.00**	5.6%	.003**
HLA-DRB1*15	7%	11.1%	.459	5.5%	.658	5.6%	.658

AT: alopecia totalis; AU: alopecia universalis; LAA: localized alopecia ateata
*statistically significant difference
**statistically highly significant difference