Serum Interleukin-4 and Total Immunoglobulin E in Nonatopic Alopecia Areata Patients and HLA-DRB1 Typing

Table 6

Comparison of the frequencies of selected HLA-DRB1 alleles in Alopecia of less and more than 1 year duration, in relation to IgE/IL-4 level using Chi square test.

Allele	Duration	High IgE/IL-4 (n & %)	Low IgE/IL-4 (n & %)	𝑥^2	P value
HLA-DRB1*07	Less than 1 year	0 (0%)	5 (83%)	8.571	.003**
	More than 1 year	6 (100%)	1 (16.7%)
HLA-DRB1*11	Less than 1 year	0 (0%)	12 (66.7%)	8.00	.005**
	More than 1 year	6 (100%)	6 (33.3%)

**statistically highly significant difference