Double-Blinded, Vehicle-Controlled Proof of Concept Study to Investigate the Recurrence of Inflammatory and Noninflammatory Acne Lesions Using Tretinoin Gel (Microsphere) 0.04% in Male Patients after Oral Isotretinoin Use

Table 1

Investigator’s Static Global Assessment.

Investigator's Static Global Assessment
0: clear skin with no inflammatory or noninflammatory lesions
1: almost clear: rare noninflammatory lesions with no more than rare papules
2: mild severity: greater than Grade 1, some noninflammatory lesions with no more than a few inflammatory lesions (papules/pustules only, no nodular lesions)
3: moderate severity: greater than Grade 2, up to many noninflammatory lesions and may have some inflammatory lesions, but no more than one small nodular lesion
4: severe: greater than Grade 3, up to many noninflammatory and inflammatory lesions, but no more than a few nodular lesions
5: very severe: many noninflammatory and inflammatory lesions and more than a few nodular lesions; may have cystic lesions