Double-Blinded, Vehicle-Controlled Proof of Concept Study to Investigate the Recurrence of Inflammatory and Noninflammatory Acne Lesions Using Tretinoin Gel (Microsphere) 0.04% in Male Patients after Oral Isotretinoin Use

Table 3

Local tolerability assessments.

Grade		Subject-assessed itching and burning/stinging
0	None	Normal, no discomfort
1	Slight	A noticeable discomfort that causes intermittent awareness
2	Moderate	A noticeable discomfort that causes intermittent awareness and interferes occasionally with normal daily activities
3	Strong	A definite continuous discomfort that interferes with normal daily activities