| Case | Age | Sex | Site | Size (cm) | Treatment (*) | CHT regimens | Surgical margin | LRec (**) | LNMet (**) | Met (**) | FU (**) | Status | EWS- ATF1 | Mitoses | Necrose | Grade | BRAF15 | NRAS 61 |
| 1 | 36 | F | Buttock | 6 | Surg+R+CT | IVA | pos | no | no | 77 | 80 | 4 | pos | 10 | 0 | 2 | neg | neg | 2 | 23 | F | Shoulder | 9 | CT+Surg+R | Adri | pos | no | no | 9 | 12 | 4 | pos | 34 | 1 | 3 | neg | neg | 3 | 11 | M | Heel | 4 | CT+Surg+R | I | neg | no | no | 23 | 40 | 4 | pos | 12 | 1 | 3 | neg | neg | 4 | 53 | F | Foot | 6 | CT+Surg+R | IVA | neg | 14 | no | 7 | 16 | 1 | pos | 6 | 1 | 2 | neg | neg | 5 | 57 | F | Forearm | 5 | Surg+R | | neg | 23 | no | no | 45 | 0 | pos | 5 | 0 | 2 | neg | neg | 6 | 23 | M | Foot | 2,5 | Surg+R+CT | MAID; MTX, C | neg | no | no | no | 11 | 0 | pos | 5 | 0 | 2 | neg | neg | 7 | 34 | F | Forearm | 4 | Surg+CT+R | Adri,I, Cispl, F, Ditic | pos | 1 | 0 | 0 | 8 | 4 | pos | 18 | 1 | 3 | ni | ni | 8 | 20 | M | Hand | 4 | CT+surg+R | Adri, DTIC, limb perf | neg | no | no | no | 28 | 0 | pos | 10 | 1 | 2 | ni | ni | 9 | 46 | F | Hand | 1,2 | Surg | | neg | 24 | no | no | 40 | 0 | pos | 5 | 1 | 2 | ni | ni | 10 | 54 | M | Foot | 3 | Surg+CT | MAID; MTX, C | pos | 1 | no | 5 | 24 | 4 | pos | 18 | 2 | 3 | ni | ni | 11 | 45 | F | Foot | 3 | Surg+R | | pos | no | no | no | 12 | ? | pos | 8 | 1 | 2 | ni | ni | 12 | 48 | M | Foot | 1,8 | Surg+R | | pos | no | no | no | 60 | 0 | pos | 3 | 2 | 3 | neg | neg | 13 | 37 | M | Foot | 2 | Surg+R+CT | 4 E+I, D | pos | no | no | 57 | 120 | 1 | pos | 2 | 0 | 2 | ni | ni | 14 | 33 | M | Leg | 4 | Surg+R+CT | 6 I | neg | no | 87 | 87 | 96 | 4 | pos | 10 | 2 | 2 | ni | ni | 15 | 31 | M | Foot | ? | Surg+CT+R | INF+Adri+T/EI | neg | no | 0 | 10 | 16 | 4 | pos | 20 | 2 | 3 | ni | ni | 16 | 37 | F | Foot | 2 | Surg+R+CT | Adri+I | pos | no | no | no | 87 | 0 | pos | 9 | 0 | 2 | neg | neg | 17 | 42 | F | Leg | 6 | Surg+CT+R | Adri+I | pos | no | 54 | no | 60 | 1 | neg | 15 | 1 | 2 | neg | neg | 18 | 51 | M | Thigh | 15 | Surg+R+CT | Adri+I+DTIC | pos | 24 | no | 33 | 60 | 4 | pos | 12 | 2 | 3 | ni | ni | 19 | 9 | M | Sacrum | 7 | Surg+R+CT | IVA | pos | 12 | no | 12 | 20 | 4 | ni | 4 | 1 | 2 | ni | ni | 20 | 31 | M | Knee | 10 | Surg+CT+R | I+C+V+DITC | neg | no | 18 | no | 20 | 4 | pos | 2 | 1 | 2 | neg | neg | 21 | 45 | M | Knee | 4 | Surg+CT+R | VACA | neg | no | no | no | 48 | 0 | ni | 3 | 2 | 2 | ni | ni | 22 | 29 | F | Foot | 3 | Surg+R | | neg | 12 | no | 16 | 40 | 4 | pos | 9 | 1 | 2 | neg | neg | 23 | 26 | M | Foot | 3 | Surg+CT+R | Adri+I | neg | 144 | no | 228 | 312 | 1 | pos | 5 | 1 | 2 | neg | neg | 24 | 38 | F | Thigh | 6 | Surg+CT+R | VACA | pos | 12 | 36 | 52 | 60 | 4 | ni | 9 | 1 | 2 | ni | ni | 25 | 17 | M | Behind bladder | 4 | Surg+CT | Adri+I | neg | no | no | no | 65 | 0 | pos | 10 | 1 | 2 | ni | ni | 26 | 6 | F | Arm | 8 | Surg+CT | V+Carbo+ epirubicin | pos | 1 | 0 | no | 180 | 0 | ni | 9 | 1 | 3 | ni | ni | 27 | 15 | F | Scapula | 5 | Surg+CT | Carbo + Adria, IL2 | pos | 10 | no | 12 | 24 | 4 | ni | 2–4 | 1 | 2 | ni | ni | 28 | 36 | M | Tibia | 3 | Surg+CT | Adri+I | pos | 16 | 20 | 22 | 28 | 4 | ni | 10 | 1 | 2 | ni | ni | 29 | 15 | F | Scapula | 5 | Surg+CT | IVA, IL2, DTIC | neg | no | no | no | 12 | 0 | ni | 4 | 1 | 2 | ni | ni | 30 | 20 | F | Scalp | 4 | Surg+CT+R | I+Adri | pos | 84 | 72 | 96 | 120 | 4 | neg | 2 | 1 | 2 | neg | neg | 31 | 33 | F | Hand | 3 | Surg+CT+R | Adri | pos | 48 | 30 | 36 | 52 | 4 | ni | 10 | 1 | 2 | ni | ni | 32 | 32 | M | Pelvis | 9 | Surg+CT+R | I+Adri | neg | 6 | 10 | 21 | 32 | 4 | ni | 10 | 1 | 2 | ni | ni | 33 | 12 | F | Foot | 3 | Surg+CT+R | IVA | pos | no | no | no | 144 | 0 | ni | 2 | 1 | 3 | ni | ni | 34 | 14 | M | Wrist | 5 à 6 | Surg+CT+R | IVA | neg | no | no | no | 120 | 0 | ni | 10 | 1 | 2 | ni | ni | 35 | 29 | M | Heel | 2 | Surg+CT+R | V+DITC+Adri +C | neg | 24 | no | 76 | 82 | 4 | ni | 19 | 1 | 2 | ni | ni | 36 | 28 | M | Wrist | 3 à 4 | Surg+CT+R | IVA, IL2, DTIC | pos | no | no | 24 | 39 | 4 | ni | 11 | 1 | 2 | ni | ni | 37 | 10 | M | Hip | 5,5 | Surg+CT+R | IVA | pos | 68 | 72 | no | 120 | 0 | pos | 18 | 1 | 2 | neg | neg | 38 | 24 | M | Foot | 3 | Surg+R | | pos | no | no | no | 156 | 0 | ni | 3 | 1 | 2 | neg | neg | 39 | 13 | M | Leg | 3 |
Surg+CT+R | VACA | neg | 30 | 30 | no | 348 | 0 | ni | 21 | 1 | 2 | ni | ni | 40 | 47 | F | Foot | 3 | Surg+CT+R | VACA | neg | 24 | no | no | 240 | 1 | ni | 12 | 1 | 2 | ni | ni | 41 | 76 | F | foot | 4 | Surg | | pos | 12 | no | 12 | 42 | 4 | ni | 2 | 1 | 3 | ni | ni | 42 | 34 | M | Wrist | 1 | Surg+CT+R | VACA | neg | 56 | no | no | 264 | 0 | pos | 10 | 1 | 2 | neg | pos | 43 | 40 | M | Leg | 4 | Surg+CT+R | VACA | pos | 60 | no | 84 | 96 | 4 | neg | 7 | 2 | 2 | neg | neg | 44 | 12 | F | Foot | 14 | Surg+R | | neg | 36 | no | no | 84 | 0 | ni | 5 | 2 | 2 | ni | ni | 45 | 73 | M | Scapula | 10 | Surg+CT+R | Adri+V+C+Plat | pos | 48 | 36 | 24 | 96 | 4 | ni | 29 | 2 | 3 | ni | ni | 46 | 20 | M | Scapula | 6 | CT+Surg+R | Adri+V+ DTIC+C | pos | 18 | 18 | 18 | 24 | 4 | pos | 8 | 1 | 2 | neg | neg | 47 | 33 | M | Foot | 5 | Surg+CT | F | pos | 16 | 4 | 4 | 31 | 4 | pos | 9 | 1 | 2 | neg | neg | 48 | 81 | F | Foot | 3 | Surg | | pos | 240 | no | 250 | 254 | 4 | ni | 9 | 2 | 2 | ni | ni | 49 | 46 | M | Foot | 4 | Surg+CT+R | I | neg | 60 | 72 | 250 | 260 | 4 | pos | 24 | 2 | 3 | pos | neg | 50 | 47 | M | Hand | 6 | Surg+CT+R | VACA | neg | no | no | 96 | 144 | 4 | pos | 15 | 2 | 2 | neg | neg | 51 | 29 | F | Foot | 2 | Surg | | pos | no | 60 | no | 60 | 1 | ni | 10 | 2 | 2 | ni | ni | 52 | 30 | M | knee | 10 | Surg+CT+R | C+V+ Adri+DTIC | pos | no | 6 | 18 | 36 | 4 | pos | 5 | 2 | 2 | neg | neg |
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((*) Surg: surgery, R: radiotherapy, CT: chemotherapy. (**) LRec: local recurrence (months), LNMet: locoregional lymph node metastasis (months), Met: distant metastasis (months), and FU: followup (months). Status: 0: alive with no disease, 1: alive with disease, and 4: died of disease. Mitoses: number of mitoses per ten high power fields. neg: negative, pos: positive, ni: not identified. Necrosis: 0: no necrosis, 1: less than 50% of necrosis, 2: more than 50% of necrosis). A: actinomycin D; Adri: Adriblastina, C: cyclophosphamide, Carbo: carboplatin, cisplt: cisplatin; DITIC: dacarbazine, EPI: eoposide, F: fotemustine; I: ifosfamide, IL2: Interleukin 2, IVA: ifosfamide (3 g/m²) + dactinomycin (1,5 mg/m²) + vincristine (1,5 mg/m²); Limb perf: regional isolated limb perfusion with melphalan and tumor necrosis factor alpha, MTX: methotrexate, MAID: doxorubicin (15 mg/m²) + dacarbazine (250 mg/m²/j) + ifosfamide (2–2,85 g/m²/j), V: vincristine; VACA: cyclophosphamide (1,2 g/m²) + doxorubicin (30 mg/m²) + dactinomycin (0,5 mg/m²) + vincristine 1,5 mg/m²; INF: intrferon; T: taxol.
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