Clinical Study

Evaluation of the Quantitative and Qualitative Alterations in the Fatty Acid Contents of the Sebum of Patients with Inflammatory Acne during Treatment with Systemic Lymecycline and/or Oral Fatty Acid Supplementation

Table 1

Distribution of patients with acne vulgaris according to the outcome of gas chromatography carried out on D0.

Fatty acid
Average% (standard deviation)Median% (min.–max.)

C12:00.32 (0.44)0 (0.00–1.39)
C13:00.02 (0.08)0 (0.00–0.45)
C14:05.79 (1.85)5.94 (1.22–10.38)
C14:10.33 (0.41)0 (0.00–1.16)
C15:03.77 (1.11)3.97 (0.88–5.45)
C15:10.01 (0.05)0 (0.00–0.34 )
C16:017.92 (5.31)17.66 (4.83–29.25)
C16:115.63 (4.86)16.73 (2.83–24.92)
C17:00.69 (0.57)0.87 (0.00–1.59)
C17:12.23 (0.93)2.36 (0.00–4.82)
C18:03.74 (1.27)3.50 (1.77–6.62)
C18:1n9c+C18:1n9t9.50 (2.59)9.83 (3.33–15.30)
C18:2n6c0.32 (0.51)0 (0.00–1.80)
C18:2n6t0.53 (1.26)0 (0.00–5.45)
C18:2n6c+C18:2n6t0.85 (1.31)0 (0.00–5.45)
C18:3n60.20 (0.73)0 (0.00–3.27)
C18:3n30.52 (1.29)0 (0.00–4.44)
C20:01.62 (5.09)0 (0.00–26.83)
C20:11.78 (4.71)0 (0.00–22.09)
C20:20.12 (0.79)0 (0.00–4.99)
C21:00.02 (0.10)0 (0.00–0.66)
C20:5n30.12 (0.75)0 (0.00–4.74)
C22:00.52 (1.47)0 (0.00–6.35)
C22:1n90.14 (0.69)0 (0.00–4.30)
C24:00.27 (0.47)0 (0.00–1.42)
Squalene13.34 (4.91)12.88 (2.88–23.15)

Total identified79.46 (14.42)84.44 (40.44–100)