Botanical Agents for the Treatment of Nonmelanoma Skin Cancer

Table 3

Summary of the effects of botanical agents investigated only in preclinical studies.

Botanical agent	Source	Efficacy	References
Curcumin	Curcuma longa Linn	Curcumin inhibits skin tumor carcinogenesis in mice.	[35–41]
Genistein	Soy, Greek sage, Greek oregano, and gingko biloba extract	Genistein inhibits skin tumor carcinogenesis in mice.	[42, 43]
Proanthocyanidin	Grape seed	Grape seed proanthocyanidins demonstrated anticarcinogenic effects against ultraviolet B-induced skin tumors in mice.	[44, 45]
Lycopene	Various plants with red pigment	Lycopene prevents photodamage in mice and humans, suggesting potential for possible prevention of NMSC.	[46, 47]