Clinical Study

Comparison the Efficacy of Fluconazole and Terbinafine in Patients with Moderate to Severe Seborrheic Dermatitis

Table 4

Comparison of itching in three-phase study.

Drugs (%) (%) (%) (%) Mean itching ± SD
Without itchingMild itchingModerate itchingSevere itching

Before treatment Fluconazole (28)0 (0%)15 (53.6%)6 (21.4%)7 (25%)1.71 ± 0.850.459
 Terbinafine (32)4 (12.5%)7 (21.9%) 11 (34.4%)10 (31.2%)1.84 ± 1.019

After treatment  Fluconazole (28)15 (53.6%)10 (35.7%)3 (10.7%)0 (0%) 0.57 ± 0.690.220
 Terbinafine (32)15 (46.9%)6 (18.8%)11 (34.4%)0 (0%)0. 87 ± 0.90

Two weeks after treatment Fluconazole (28)16 (57.1%)9 (32.1%)3 (10.7%) 0 (0%)0. 53 ± 0.690.773
 Terbinafine (32)18 (56.2%)14 (43.8%)0 (0%)0 (0%)0. 43 ± 0.50

 *Mann-Whitney test.