Epidermal Permeability Barrier in the Treatment of Keratosis Pilaris

Table 1

At the end of the 12-week treatment period, the obtained skin conductance values were significantly higher for each of the therapies, as compared with their respective baseline values. These obtained values were higher for the 10% lactic acid cream treated side than the 5% salicylic acid treated side. By contrast, TEWL showed no statistically significant changes in both lactic acid and salicylic acid-treated sites as compared with those values measured before treatment.

	Conductance (±SD)		TEWL (±SD)
	10% lactic	5% salicylic	10% lactic	5% salicylic
Base line	121.5 ± 60.0	124.5 ± 55.3	8.1 ± 1.6	7.9 ± 1.8
Week 12	169.1 ± 74.0^*	148.5 ± 49.9^*	7.7 ± 1.6	7.7 ± 1.4
4-week follow-up	155.3 ± 53.2^*	140.6 ± 43.6^*	7.5 ± 2.3	7.7 ± 1.2

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