Research Article

Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital

Table 5

Treatment outcomes according to supportive care alone versus systemic treatment.

Supportive care only, N = 8Systemic treatment, N = 28P value

Length of hospital stay (d) (mean ± SD)9.9 ± 7.412.3 ± 11.40.593

Comorbidities/short-term complication, N (%)
 Skin
  Dyspigmentation5 (62.5)21 (75.0)0.486
  Nail change04 (14.3)0.257
 Eye5 (62.5)19 (67.9)0.777
  Conjunctivitis3 (37.5)14 (50.0)0.532
  Corneal epithelial defects2 (25.0)4 (14.3)0.473
  Synechiae/symblepharon2 (25.0)4 (14.3)0.608
  Pseudomembrane1 (12.5)5 (17.9)0.720
 Superinfection1 (12.5)9 (32.1)0.532
 Vaginal adhesion1 (12.5)2 (7.1)0.629
 Pneumonia1 (12.5)1 (3.6)0.331
 Pancreatitis01 (3.6)0.588
 Adrenal insufficiency01 (3.6)0.588

Long-term sequel, N (%)
 Skin4 (50.0)15 (53.6)0.261
 Eye5 (62.5)8 (28.6)0.302
 GI (transaminitis)2 (25.0)6 (21.4)0.795

Recurrence, N (%)01 (3.6)0.588