Confocal Microscopy Predicts the Risk of Recurrence and Malignant Transformation of Mucocutaneous Neurofibromas in NF-1: An Observational Study

Table 1

Characteristics of the studied population and relative CLSM data.

Age	Sex	Excised neurofibroma site	Excised neurofibroma histo-type	Oral lesions	NF family history	Comorbidities	Recurrence	Time of recurrence (years)	Malignant degeneration	Schwann cells fluorescence
31	m	trunk	plexiform	x	x	advanced melanoma	x (regression with chemo)	6		none
47	f	lower limbs	subcutaneous/nodular							high
47	f	upper limb	diffuse	x			x	4	x	none
26	m	lower limbs	plexiform		x					high
42	f	upper limb	diffuse	x	x					high
73	f	trunk	plexiform	x		arterial hypertension, diabetes				high
44	m	trunk	Subcutaneous/nodular		x					high
16	m	oral	plexiform	x						high
59	f	upper limb	Subcutaneous/nodular	x			x	8		minimal
46	f	oral	plexiform	x						high
53	f	lower limbs	diffuse		x					high
53	f	face	plexiform			hypothyroidism				high
35	f	trunk	diffuse				x	7		none
41	m	oral	Subcutaneous/nodular	x	x					high
55	2	trunk	plexiform	x	x	arterial hypertension	x	3	x	none
50	2	face	diffuse	x						high
42	2	lower limbs	Subcutaneous/nodular		x					high
43	1	upper limb	plexiform	x						high
51	2	oral	Subcutaneous/nodular	x	x	arterial hypertension	x	5	x	none
47	2	lower limbs	plexiform		x					high