Is Oral Omega-3 Effective in Reducing Mucocutaneous Side Effects of Isotretinoin in Patients with Acne Vulgaris?

Table 2

Comparison of the frequency of mucocutaneous side effects of isotretinoin between case and control groups.

	Isotretinoin; group (%)	Isotretinoin + omega-3; group (%)	value
Dry lips
Baseline	0	0
Week 4	78.7	58
Week 8	64.8	50
Week 12	44.4	26
Week 16	25.6	14
Dry nose
Baseline	0	0
Week 4	33.3	12
Week 8	24.1	10
Week 12	14	2
Week 16	11.1	0
Dry skin
Baseline	0	0
Week 4	40.7	16
Week 8	22.2	10
Week 12	18.5	8
Week 16	11.1	2
Dry eyes
Baseline	0	0
Week 4	13	4
Week 8	9.3	6	0.533
Week 12	3.7	0	0.169
Week 16	0	0	1.00

values less than 0.05 were considered significant.