Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study

Table 1

Baseline demographics and clinical characteristics of patients with melisma.

Gender, No. (%)
Female	49 (89.1)
Male	6 (10.9)
Age, years
Mean± SD	35.93±5.9
(Range)	(27-51)
Duration of disease , years
Mean± SD	6.24±2.7
Fitzpatrick’s skin type; N (%)
2	9 (16.4)
3	35 (63.3)
4	11 (20)
Family history; N (%)
Positive	28 (50.9)
Negative	27 (49.1)
History of oral contraceptive intake; N (%)
Positive	30 (54.5)
Negative	25 (45.5)