Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study

<table class="fixed-width table-group" id="tab2"><tr><td><table class="table"><colgroup><col style="width:10.75em"/><col style="width:8.99em"/><col style="width:7.45em"/><col style="width:4.38em"/></colgroup><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2"> </td><td class="align_center"><b>Tranexamic acid +</b></td><td class="align_center" rowspan="2"><b>Hydroquinone</b></td><td class="align_center" rowspan="2"><b>p-value</b></td></tr><tr class="thead"><td class="align_center"><b>Hydroquinone</b></td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left"><b>Baseline MASI Score</b></td><td class="align_center" rowspan="2">5.165±1.875</td><td class="align_center" rowspan="2">5.204±1.935</td><td class="align_center" rowspan="2">0.08</td></tr><tr><td class="align_left"><b>(Mean</b>±<b>SD)</b></td></tr><tr><td class="align_left"><b>MASI Score in week 16</b></td><td class="align_center" rowspan="2">1.769±0.981</td><td class="align_center" rowspan="2">2.926±1.219</td><td class="align_center" rowspan="2">0.001</td></tr><tr><td class="align_left"><b>Mean</b>±<b>SD</b></td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>MASI score before and after treatment in two groups.</div>

Dermatology Research and Practice

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Table 2

Table 2: Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study 

Table 2 | Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study 