Comparison of the Efficacy and Safety of Two Cryotherapy Protocols in the Treatment of Common Viral Warts: A Prospective Observational Study

Table 2

Response to treatment (cure and side effects) in both treatment groups.

	Protocol 1; N = 45		Protocol 2; N = 35		‐value
	n/N	(%)	n/N	(%)
Cure rate (out of the total number) (intention to treat (ITT))	35/45	77.8	19/35	54.3	0.001
Cure rate (out of the number who completed the study) (per protocol (PP))	35/37	94.6	19/30	63	0.026
Number of warts cleared	91/113	86	55/84	69	0.038
Mean number of sessions to cure	2.5		1.8		0.054
Average pain score	5.2		6.4		0.004
Blisters	9/45	21	11/35	31	0.247
Hypopigmentation	8/45	18	10/35	29	0.251
Recurrence	5/35	14	4/19	21	0.532