Combination Therapy with 1% Nanocurcumin Gel and 0.1% Triamcinolone Acetonide Mouth Rinse for Oral Lichen Planus: A Randomized Double-Blind Placebo Controlled Clinical Trial

Table 2

Comparison of the REU scores at baseline and at two and four weeks.

Time	Observed mean REU		Adjusted mean REU		Adjusted mean difference
	Nanocurcumin	Placebo	Nanocurcumin	Placebo	Mean (SE)	value
	Mean (SD)	Mean (SD)	Mean (SE)	Mean (SE)
Baseline	20.39 (8.54)	16.00 (8.48)				0.163
Two weeks	11.04 (7.32)	12.26 (7.09)	9.09 (0.62)	13.86 (0.54)	−4.77 (0.83)	<0.001^$
Four weeks	7.21 (5.42)	10.44 (6.51)	5.71 (0.81)	11.67 (0.74)	−5.93 (1.12)	<0.001^$

Baseline REU values are taken as covariates for the adjusted model. ^$P values are based on comparing the adjusted mean values.