Clinical Study

Combination Therapy with 1% Nanocurcumin Gel and 0.1% Triamcinolone Acetonide Mouth Rinse for Oral Lichen Planus: A Randomized Double-Blind Placebo Controlled Clinical Trial

Table 3

Comparison of the improvement level and the efficacy index at two and four weeks between the two groups.

Two weeksFour weeks
Nanocurcumin n(%)Placebo n (%) valueNanocurcumin n (%)Placebo n (%) value

Healed0 (0%)0 (0%)<0.0010 (0%)0 (0%)0.001
Marked improvement2 (14.3%)0 (0%)7 (50%)1 (5.9%)
Moderate improvement11 (78.6%)3 (17.6%)7 (50%)9 (52..9%)
No improvement1 (7.1%)14 (82.4%)0 (0%)7 (41.2%)

EI mean (SD)54.60 (17.05)24.63 (11.71)<0.00163.04 (13.94)36.46(17.53)<0.001