aMCID for these studies was obtained from a study that measured the MCIDs of SCORAD, EASI, and POEM for atopic eczema by Schram et al. . bData were not adequate to calculate the confidence interval. cResult was reported using a nonparametric statistic, and no confidence interval was reported. Converted result into parametric data was retrieved from a systematic review . dMean reduction between two groups was extracted from a systematic review that had transformed the result into parametric data beforehand. MCID for VASP that is specific for eczema has never been investigated .