Research Article

Cosmetic Syndrome Correction with Calcium Hydroxylapatite-Based Filler in Patients with Connective Tissue Dysplasia

Table 1

Developmental abnormalities corresponding to CTD-related cosmetic syndrome [9].

SignsFrequency (%)

Morton’s toe (the 2nd toe is longer than the 1st)52.0
Sandal cleft in foot (distance between the 1st and the 2nd toes is ≥ the width of the 2nd toe)52.0
Compromised dentition41.0
Clinodactyly (curvature of a digit)26.0
Third type of earlobe (adherent earlobe)22.0
Malocclusion22.0
Low hair growth on the forehead and neck19.0
Extra teeth14.5
Heterochromia iridis11.5
Tongue-tie10.5
Low-set ears8.0
Diastema (wide gap between the central incisors)8.0
Upper lip frenulum8.0
Deformed ears7.5
Hypotelorism (close-set eyes)7.0
Big sticking-out ears7.0
Epicanthic fold (skinfold in the medial canthus)6.5
Exophthalmos6.5
Enophthalmos6.0
Ocular hypertelorism (increased distance between the inner eye corners)5.0
Crumpled-ear deformity5.0
Nipple hypertelorism4.5
Camptodactyly (contracture of the proximal interphalangeal joint)2.0
Brachydactyly1.5
Polythelia (more than 2 nipples)1.0